A Biochemical Characterization of Histidine-dependent Mutants of Staphylococcus Aureus.
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چکیده
منابع مشابه
Transduction Analysis of the Histidine Region in Staphylococcus Aureus.
The genetic control of histidine biosynthesis in Staphylococcus aureus was examined by an analysis of 66 histidine-dependent mutants by using stable and abortive transduction. These mutants, which previously had been differentiated into classes according to their biochemical characteristics, all occupied sites within a single linkage group, referred to as the histidine region. This region has b...
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The SaeRS two-component regulatory system of Staphylococcus aureus is known to affect the expression of many genes. The SaeS protein is the histidine kinase responsible for phosphorylation of the response regulator SaeR. In S. aureus Newman, the sae system is constitutively expressed due to a point mutation in saeS, relative to other S. aureus strains, which results in substitution of proline f...
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Staphylococcus aureus cause infections by producing toxins, a process regulated by cell-cell communication (quorum sensing) through the histidine-phosphorylation of the target of RNAIII-activating protein (TRAP). We show here that TRAP is highly conserved in staphylococci and contains three completely conserved histidine residues (His-66, His-79, His-154) that are phosphorylated and essential f...
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ورودعنوان ژورنال:
- Journal of general microbiology
دوره 39 شماره
صفحات -
تاریخ انتشار 1965